It’s not always candida!
Gut microbiome
We can think of microbiomes as communities of microbes. The gut microbiome is made up of around 1,000 different types of bacteria. These can be divided into as many as 400 species and subspecies. Every human being harbours at least 160 species that are directly or indirectly involved in physiological processes such as metabolism, immunity and protection against other pathogens. (Goeser F., 2012)
Gut bacteria are essential for
– digestion,
– synthesis of vitamins and amino acids, and
– boosting the immune system.
Each person has an individual gut bacterial composition, which is formed in childhood and later evolves according to diet and lifestyle.
The microbiome can be classified further according to:
1) diversity,
2) dysbiosis
3) metabolicprocesses
1. Diversity
Microbiome diversity relates to the number of different bacterial strains dominant in the gut environment. The simplest version of a definition would be the more microbial species live together the more diverse the gut community is. Microbiome diversity also represents the stability of bacterial coexistence in the gut and it ́s resistance to colonisation by fungi or bacteria that produce dangerous toxins. Interestingly, no two micro-biomes were identical in any samples examined so far.
The diversity of the microbiome is influenced by birth (vaginal flora, colostrum, caesarean section, etc.), breast milk or formula milk, general dietary habits, the use of antibiotics and other toxins or stimulants (alcohol, drugs), stress and many other factors.
A poorly diverse gut flora results in reduced synthesis of vitamins and short-chain fatty acids. This can lead to mis-colonisation by pathogens or fungi and a gut that is more susceptible to diseases such as irritable bowel syndrome, food intolerances, chronic inflammatory bowel diseases and infections, impaired neurological function of the gut, and various behavioural patterns (depression, anxiety, etc.).
2. Dysbiosis
Dysbiosis is defined as a dysbalance of the gut microflora that is further associated with various diseases. Evidence supports that rather than one or two dominant organisms inducing host health, it is the composition of the entire community of microbial residents that influences a balanced immune response. Thus, disturbances to the structure of these complex commensal communities (referred to as dysbiosis) can lead to a deficient “education” of the host immune system and the subsequent development of diseases.
Here we see how micro-organisms are typically distributed throughout the gut.
The stomach and duodenum contain relatively few microorganisms. In the small intestine, the diversity of species and the number of microorganisms gradually increases from the proximal jejunum to the terminal ileum, with anaerobic components of the flora becoming increasingly important.
A good third of the total mass of faeces is made up of excreted intestinal bacteria, with the vast majority (99%) being anaerobes (Bacteroides, Bifidobacteria, Eubacteria, etc.). On the other hand, aerobic or facultatively anaerobic micro-organisms account for barely more than 1% of the bacterial mass (Escherichiae and Enterococci in particular).
3. Metabolic and allergic processes in the gut
The gut undergoes various metabolic actions, which may depend on the prevalence of microorganisms or on a general allergic reaction.
They are divided into:
a) Fermentation
b) Rotting / proteolysis
c) Classic allergic reactions and intolerances
a) Fermentation
Yeasts and lactic acid bacteria are mainly responsible for the fermentation process
in our digestive tract. This is a metabolic process that breaks down carbohydrates/sugar with the help of enzymes and in the absence of oxygen produces ATP energy. The process also produces lactic acid, which is further fermented by lactic acid micro-organisms.
b) Rotting / proteolysis
The amount of protein in the colon is associated with an increase in the number of putrefactive bacteria and metabolites and a decrease in the number of carbohydrate-fermenting bacteria (Toden et al., 2007; Lubbs et al., 2009). Unlike the fermentation of carbohydrate-based fibre in the large intestine, which is considered beneficial or benign, microbial putrefaction of protein can be harmful. In the fermentation of fibre, commensal microbes produce beneficial metabolites, including short-chain fatty acids (e.g. butyrate, which serves as the primary energy source for the colonic epithelium) and some vitamins. In addition to serving as an energy source, short-chain fatty acids also lower intraluminal pH, which inhibits the growth of pathogens. Similar to the fermentation of fibre, some short-chain fatty acids are also produced during putrefaction. However, unlike fibre fermentation, putrefactive bacteria produce a number of metabolic by-products, including ammonia, sulphides and biogenic amines (histamin). These metabolites reduce the persistence of colonic epithelial cells, increase intestinal cell permeability, cause DNA damage and inhibit cellular respiration and proliferation.
The amount of putrefaction in the colon also depends on the amount of fibre in the diet. Unlike most starches and small sugars that are absorbed in the small intestine, fibre survives to the large intestine where it can serve as a source of carbon for the micro-organisms of the large intestine. Since carbohydrates are the preferred food for gut microbes, protein putrefaction occurs only after most dietary fibre has been fermented. As a result, putrefaction is all the more likely the further away the colon is.
Adding fibre to the diet can therefore reduce putrefaction. This said therefore supplementing the diet with fibre only postpones the putrefaction in the gut. It is more optimal to opt for a low-protein diet as the harmful metabolite level itself is then lowered. I am giving the full theory of protein digestion because in practice we are faced with the complex issue of nutrition counselling, which is a very complex area. On the one hand, we test a patient for increased candida colonisation, and remove simple carbohydrates from the diet. However on the other hand it is important to not remove fibre and increase animal protein intake, otherwise we may accelerate the very reverse process in the gut.
Toxic metabolites ‐ HistaminHistamine is an important metabolite of gut bacteria as it plays a central role in allergic reactions and mediates inflammatory processes.Increased histamine concentrations in faeces may be due to (a) insufficient DAO (diaminoxidase) activity, (b) increased dietary histamine intake, or (c) increased gut putrefactive activity of certain gut bacteria. Different species of proteolytic (putrefactive) gut flora, such as Hafnia alveii, Klebsiella, Enterobacter, Serratia, Citrobacter, E. coli or Morganella, are responsible for the synthesis of histamine from protein foods as well as for the activation of histamine from mast cells in the intestinal mucosa, depending on their metabolic capacity.
It is difficult to distinguish between the three sources of increased histamine activity in the gut and consequently in the body, based on the patient’s clinical symptoms alone. BICOM bioresonance can therefore be used for orientation diagnostics as well as for the treatment of such deviations, as we strive to reduce dietary histamine intake and increase the diversity of the gut microbiome.
c) Classic allergic reactions and intolerances
The gut is also the site of classic allergic responses, which are triggered by individual allergens and result in elevated IgE antibodies. We will not break them down here, but only mention them for the purpose of distinguishing the different processes that may be occurring in the body and that should be considered when using BICOM bioresonance.
For example, a wheat allergy with high IgE antibodies is a type I hypersensitivity reaction. This said, we also have non-celiac wheat sensitivity (NCWS), where again the dysbiosis of gut bacteria (mainly a large increase in Escherichia, Klebsiella and Pseudomonas) plays a decisive role. In such cases we do not find an increase in IgE antibodies, in spite of sensitivity.
BICOM bioresonance testing and therapy for intestinal problems
BICOM bioresonance testing allow us to better orient patients with intestinal symptoms about possible processes in the digestive tract. As we have seen, we can have several possible reasons for a patient’s problems. Therefore, we are first interested in the type of metabolic process that is involved in the intestine. So we ask ourselves:
Is the intestine undergoing predominantly classical sugar fermentation? Candida growth suspected.
Is the gut undergoing predominantly putrefactive protein fermentation? Suspected growth of proteolytic bacteria and metabolites such as histamine.
Are there hypersensitivity reactions in the gut?
Negative IgE and clear clinical signs may suggest different food sensitivities or genetic enzyme deficiencies.Do classic allergic IgE reactions take place in the gut? High IgE antibodies to allergens.
Of course, I would just like to mention acute abdominal viruses and other intestinal problems that we also need to think about, although I will not mention these in this paper because of time constraints.
In patients with a clinical picture of intestinal problems, the pink ampules from the “ 5- Element” test kit can already give an indication of the stresses in the body. This in turn can point us towards possible occurences in the gut:
The CTT test kit “Allergic Strains” gives us additional information about intolerances. Although this cannot tell us for sure whether it is a classical allergy (only blood tests for high IgE antibodies can confirm this), it can tell us a lot about other possible intestinal processes:
The body’s reaction to histamine Dysbiosis, inflammatory reaction, allergy?
Reaction to protein Over-intake, dysbiosis, hypersensitivity?
Reaction to carbohydrates Too much intake, fermentation, candida, allergy?
Reaction to yeast (also check for Candida) Candida growth?
Probable classical allergy High IgE?
If the following ampules are tested in the CTT test kit “Allergic Strains”, we can narrow down our differential diagnosis of intestinal problems:
We are also interested in the intestinal bacterial flora. A bioresonance test can give an indication of possible dysregulation of putrefactive bacteria in the gut. These are highlighted in red.
To make our bioresonance test even more specific, it is useful to add previously tested ampules from the CTT test kit “Allergic Strains” (histamine, proteins, carbohydrates or others) to the input cup.
Case studies from BICOM bioresonance practice
Case study 1
A 41-year-old man has a known diagnosis of ulcerative pancolitis and later developed cytomegalovirus colitis. Despite high levels of biologic drug, he has frequent and severe reactivations of the underlying disease. Several biologics have been changed, but he still has bloody stools and painful diarrhoea. He has very frequent headaches. There is no family history of chronic inflammatory bowel disease. He occasionally takes the analgesic Nalgesin. He has a history of periodontal disease, which is currently in remission. A few months ago he received antibiotic therapy.
The electroacupuncture test elevated the Nerve System 60 and Metabolism 60 meridians, corresponding to the Earth element.
The patient’s test was as follows:
Dental focci
Impaired excretion, liver strain
Allergic strains: protein, gluten, sweeteners, nuts
Viral loads
We also determined the state of the microbiome through stool analysis to monitor our therapies.
Stool results indicate a putrefactive environment. The putrefactive bacteria mainly metabolise proteins and fats and produce toxic, alkalising metabolites that can cause long-term damage to the intestinal mucosa. The metabolic products produced in the intestine are detoxified by the liver, which can put a considerable strain on the liver (endogenous poisoning). Lactic acid protection is also reduced, which in turn promotes the proliferation of pathogenic microbes due to reduced resistance to colonisation. This constellation results in an increase in the pH of the intestine and conditions are provided for the further development of pathogens.
An increase in Enterobacter strains has been detected, which is particularly prone to produce endotoxin, which can cause diarrhoea, as well as significantly increasing histamine levels in the intestinal lumen. Depending on the concentration of histamine in the lumen, symptoms of histamine intolerance can occur, such as headache, migraine, dizziness, flatulence, diarrhoea, constipation, nausea, vomiting, abdominal pain and other high blood pressure, palpitations, heart palpitations, cardiac arrhythmia, menstrual cramps, joint pain, exhaustion, fatigue, sleep disturbances and even asthma at- tacks. Our patient had quite a few of these.
Reduced numbers of Enterococci and Lactobacilli indicate a disturbed microbial environment and reduced resistance to colonisation. Enterococci are part of the obligate murine intestinal flora of the small and large intestine and regulate the pH of the intestine by producing short-chain fatty acids. This means that Enterococci have an antagonistic function against putrefactive bacteria in the small intestine.
The patient also has other markedly elevated inflammatory parameters indicating active colitis, including leaky gut (elevated alpha-1-antitrypsin), and poor mucosal immunity (low IgA levels). There is also a possible allergic reaction in the gut (elevated EPX).
The patient’s BICOM therapies were long-term and focused on supporting the elimination organs, mainly the liver. Therapy was focused on gluten and Enterobacter as well
as beta herpes (CMV virus), all of which were treated with Ai parameters. It is a good idea to add a histamine ampule to gut bacteria therapy. Enterococcus deficiency was stimulated by channel 2, where Symbioflor 2 was selected. Symbioflor 2 can also be purchased and taken daily on a regular basis alongside other probiotics which are suitable for histamine-sensitive patients. The enterococcal fatty acid metabolite “butyrate” can also be taken.
A significant number of therapies were carried out in 2017 (Fig. 10) and 2018 (Fig. 9 and 10). Since the beginning, his condition has stabilised significantly, with no bloody streaks or painful diarrhoea. However as his condition has always fluctuated to some extent we continued to carry out maintenance therapies regularly, focusing on the regulation of the proteolytic flora in the intestine. The patient was on a protein-free and gluten-free diet at all times.
At the time of the second analysis (see Fig. 10 – 24.7.2017), we can see the parameters of ulcerative colitis are within the normal range. At that time, I performed BICOM therapy of viruses, mainly CMV, on the patient. However, at the time of the third analysis (fig. 9 and 10 – 29.3.2018), elevated calprotectin and sIgA values showed and the patient also had a cold. It is known that biologic drugs can reactivate or even trigger CMV infection – which are possible interpretations of the extremely high levels of secretory IgA, which represents mucosal immunity. Continuation of bioresonance therapies with the ampule beta herpes (CMV) would be very reasonable in view of the mentioned side effects of biologics.
Case study 2
The 62-year-old academic professor has been treated with bioresonance in the past for intestinal problems. At this time the treatment was aimed at controlling candida. She now comes to our practice complaining of a feeling of heavy bowels, with just a glass of water causing bloating. She has frequent panic attacks and then her bowel problems get worse. She is often constipated and has difficulty passing stools. She has already eliminated gluten, lactose and eggs and notices that she is not very comfortable with meat. Despite all the food she has eliminated, the problems are still present. She had frequent angina during her childhood, which was treated with antibiotics. She also received two doses of Astra Zeneca’s SARS-Cov-2 vaccine in 2021. Of her medications, she takes Cymbalta and Trittica for a depressive condition with occasional panic at- tacks. Sleep is satisfactory.
The electroacupuncture test showed a weak energy state of the lung meridian, corresponding to the metal element and depletion due to intestinal problems.
The patient’s test of the pink ampules in the CTT test kit “5-Elements” was as follows (where more detailed ampules are not given, we did not perform the test at the first examination, we only performed the test of the kits we considered first):
a) Allergic strains: protein, wheat
b) Bacteria: gut bacteria
c) Parasites
d) Vaccine: Astra Zeneca vaccine
We also determined the state of the microbiome through stool analysis to control our tests and to make our approach even more effective.
Figure 11: Laboratory results 22.10.2021
The patient has a typical picture of an increased putrefaction process due to increased colonisation with E.Coli. This is part of the obligatory flora of the colon in humans, but must have a normal number of bacteria, and a reduced number of protective flora, without a severe increase in inflammatory parameters and without the development of leaky gut. She was advised to follow a protein-free diet, which means avoiding all animal proteins, and a wheat-free diet, while other gluten products could be consumed.
BICOM bioresonance therapy was based on restoring a normal gut microbiome. Thus, we performed Ai therapies in combinations of wheat ampules, histamine (as a metabolic product of protein breakdown) and E.Coli, as well as other gut bacteria that came into resonance. The parasites were treated but were of minor importance as the condition had already started to stabilise.
Figure 12: Continuation of the report 22.10.2021
We added Symbioflor 2 due to low Enterococci colonisation and Smidge probiotic for histamine-sensitive patients. In this patient, who has a very active neuro-intestinal axis, it was also important to add B6, zinc and copper as essential micronutrients for both neurotransmitter regulation and good DAO function, as well as for the establishment of gut microflora.
Once the bowel condition stabilised, we started detoxification therapies. Now the patient is stable with the support of nutritional supplements. In particular, with Symbioflor 2, we reduced it to an adequate concentration over time. As she realised the impact of the gut on her psychophysical state, and has decided that she would like to come off psychiatric medication. This is our next stage in further therapies and another topic for a future congress.
Case study 3
A 36-year-old psychotherapist has had abdominal pain with cramps, bloating, alternating constipation with diarrhoea for a year and a half. He also has severe pain under the left rib arch, especially in a sitting position. 5 months ago he received antibiotics for H. Pylori. He is currently taking the antibiotic Xifaxan (rifaximin) for diarrhoea, as well as Analgin and Spasmex as needed. He has lost 19kg. He eats a balanced diet, free from gluten, dairy and alcohol. A month ago he had COVID with a severe cough. In 2021 he was vaccinated with the Moderna vaccine against SARS-Cov-2. He feels extremely exhausted because of all the problems. The patient also suffers from seasonal allergies to pollen from April to June.
The electroacupuncture test showed a weak energy state of the colon meridian and nervous system.
The patient’s test of the pink ampoules from the CTT test kit “5Elements” was as follows (where no ampules are specified, we did not perform the test at the first examination, we only performed the test of the kits that we considered first):
a) Allergic strains: histamine, pollens
b) Bacteria: gut bacteria (Enterococci, Salmonella, Escherichia, Campylobacter)c) Degenerated cells
d) Parasites, Environmental Loads
e) Intercellular tissue strainWe also determined the state of the microbiome through stool analysis to control our test and to make our approach even more effective.
Despite the subjectively severe course of the intestinal problems, the patient’s laboratory picture does not show severe inflammatory processes, but rather increased Citrobacter colonisation and decreased E.Coli flora. Given that the patient is allergic, histamine expression and action is already more pronounced in the body. In this case histamine-rich food caused more problems, with additional histamine production as a metabolic product of the proteolytic flora (elevated Citrobacter). The reduced E.Coli levels can be attributed to the antibiotic Xifaxan, which is the drug of choice for travel diarrhoea due to E.Coli and for IBS with concomitant diarrhoea.
BICOM bioresonance therapy was primarily aimed at regulating the intestinal bacterial flora, so we ran Ai programs with Citrobacter ampules in combination with histamine and other intestinal bacteria that were in resonance. E.Coli was not run on Ai, but added to channel 2 as Symbiflor 1, which is found among the channel 2 substance complexes.
The patient chose to take an antihistamine in addition to bioresonance therapy. He also introduced a histamine-poor diet and takes DAOSIN enzyme occasionally and pro-biotics suitable for histamine-sensitive patients on a regular basis.
He came to his fourth treatment smiling, with no diarrhoea and no pain under his left rib arch. He says he is full of energy, has improved focus and is no longer cold in his hands and feet. Despite the pollinosis season, he breathes easier and sleeps through the night without nasal congestion.
Conclusion
In this talk, I wanted to give you a different view of what is happening in the gut and how to approach it with CTT kits. In particular, over the last years I have been looking for a way to orient my bioresonance practice in the diagnosis of bowel problems.
We have realised that candida is not always and necessarily the culprit for all problems. The most common changes in the flora include an increase in aerobic Gram-negative bacteria (Escherichia coli, Enterobacter, Citrobacter, etc.), accompanied by a de-crease in lactic acid flora and perhaps an increase in fungi or clostridia. The stability of the microbiological environment is therefore very important for digestion. The production of toxic metabolites has a detrimental effect on the mucosa and eventually leads to damage of the intestinal mucosa. Changes in the faecal flora are not specific to particular causes or diseases, but the extent of the changes may suggest the severity of the underlying disorders.
With BICOM bioresonance therapy, we have an excellent method of treatment without any harmful side effects.
Literature
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